Recombinant YY1 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: E-AB-81623-50, E-AB-81623-100

Citations, Manuals and MSDS Available upon request.

Abbreviation: YY1

Target Synonym: CF1; Delta; Delta transcription factor; INO80 complex subunit S; INO80S; NF E1; NF-E1; NFE1; OTTHUMP00000197459; Transcriptional repressor protein YY1; TYY1; UCR motif DNA binding protein; UCRBP; Yin and yang 1; Yin and Yang 1 protein; Yin Yang 1; Ying Yang 1; YY 1; YY 1 transcription factor; YY-1; YY1; YY1 transcription factor

Research Areas: Cancer, Epigenetics and Nuclear Signaling, Neuroscience

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: WB

Isotype: IgG

Clonality: Rabbit Monoclonal

Clone No.: R02-8A3

UNIProt ID: P25490

Background: YY1, also named as DELTA, INO80S and NF-E1, contains four C2H2-type zinc fingers and belongs to the YY transcription factor family. YY1 is a multifunctional transcription factor that exhibits positive and negative control on a large number of cellular and viral genes by binding to sites overlapping the transcription start site. YY1 may direct histone deacetylases and histone acetyltransferases to a promoter in order to activate or repress the promoter, thus implicating histone modification in the YY1. The open reading frame of the human YY1 cDNA encodes a protein of 414 amino acids with a predicted molecular weight of 44 kDa. However, YY1 migrates on SDS gels as a 65–68 kDa protein, probably due to the structure of the protein. It is a ubiquitously expressed transcription factor with fundamental roles in embryogenesis, differentiation, replication and proliferation.

Concentration: 300 μg/mL

Immunogen: A synthetic peptide of human YY1

Buffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

Purification Method: Affinity Purified

Dilution: WB 1:1000-1:2000

Calculated MW: 45kDa

Observed MW: 65kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only